Which dose should I start with — 12.5mg or 20mg?+
If you've never taken methylene blue, start with 12.5mg (or 8mg for the most gradual introduction). The starter strength lets you titrate up and assess your tolerance. Many users move to 20mg after a period of consistent lower-dose use. If your healthcare provider has recommended a specific dose, follow their guidance.
When should I take methylene blue?+
Most users take it in the morning with a meal containing fat — the tallow-based capsule is fat-soluble, so dietary fat supports absorption. Many prefer to dose earlier in the day rather than close to bedtime. Consistency at the same time each day matters more than the exact hour. Follow your clinician's guidance on timing.
Why tallow-based instead of plant-based?+
Methylene blue is lipophilic — it's more soluble in fat than in water, so a fat-based carrier suits the molecule. Grass-fed beef tallow provides a stable, naturally fat-soluble delivery system without the rancidity issues common in plant-oil capsules and without synthetic emulsifiers. Our tallow is sourced from grass-fed, pasture-raised cattle in the USA.
What can I expect to feel?+
We don't make health claims about what methylene blue will or won't do — effects vary by individual, and any expectations should come from your own healthcare provider in the context of your protocol. What we're responsible for is what's in the capsule: pharmaceutical-grade USP methylene blue at the labeled dose, verified by the lab report on your bottle. For guidance on what to expect for you specifically, talk to your clinician.
Will my urine turn blue?+
Yes — this is a known and harmless effect of methylene blue. Urine may appear blue or blue-green for several hours after dosing as the compound is excreted. Some users also notice a temporary blue tint to the tongue if a capsule is bitten or opened. Both are cosmetic and resolve completely — and they're one of the most distinguishing features of authentic methylene blue.
What medications interact with methylene blue?+
Methylene blue acts as a monoamine oxidase inhibitor (MAOI) at higher doses and can cause serotonin syndrome when combined with serotonergic medications — including SSRIs, SNRIs, tricyclic antidepressants, MAOI antidepressants, lithium, tramadol, MDMA, and certain migraine medications. Do not take methylene blue if you are on these medications without explicit clinical supervision. Also avoid if you have G6PD deficiency (risk of hemolytic anemia) or are pregnant or nursing. When in doubt, ask your physician first.
How do I verify my batch is legitimate?+
Every bottle ships with a QR code on the label. Scan it with your phone to open the live laboratory report for your exact lot — current to the batch, never archived. The report verifies identity, purity, potency, heavy-metal content, and microbial safety. If a methylene blue product can't show you a lot-specific COA, that's a serious red flag.
How long does one bottle last?+
Each bottle contains 60 capsules. At one capsule daily, that's a 60-day supply. The 20mg Value Pack contains 180 capsules across 3 bottles — a six-month supply at one capsule daily, and the most cost-effective option for sustained daily use.